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KMID : 0603520010060030148
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Journal of Korean Association of Cancer Prevention
2001 Volume.6 No. 3 p.148 ~ p.154
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Prospective Study on Risk Factor for Cancer Age in Mass Screening
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Kim Yun-Jin
Chang Chul-Hun
Son Han-Chul
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Abstract
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To evaluate the effectiveness of tumor markers by 7 independent tumor markers for early detection of risk group, we surveyed the data for the geriatric health screener and the continuous follow-up test in the patients who visited the health promotion center of Pusan national university hospital and summarized as follows. 1. In the health screening, there is no evidence of effectiveness of AFP, CEA, CA125, and PSA for the screening. 2. It is useful to screen primarily with broad-spectrum tumor markers and then, in case of positive results, to perform the profile of the organ-specific tumor markers.
3. As a tool of primary screening, combination assay of the broad-spectrum tumor markers like Giftec, polyamine, and LDH is more effective. To summarize the results above and literature reviewed, it is suggested that combination assay of broad-spectrum tumor marker is more suitable for the early detection of risk group and carry out the organ specific tumor markers in the risk group selected based on the results of the primary broad-spectrum tumor markers and associated factors by consequent order. It will be benefit for financial and personal aspect.
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KEYWORD
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Early detection of cancer, Tumor marker, Combination assay
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